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Archive for April 2012

Cholera loves chitin

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The Broad Street pump

This post was chosen as an Editor's Selection for ResearchBlogging.org

Last year, I was lucky enough to visit the Wellcome Collection’s Dirt exhibition, which featured several microbiology treasures. Among other objects, I saw an original van Leeuwenhoek microscope and a first edition of Robert Hooke’s Micrografia. I also had the chance to get close to an original copy of John Snow’s cholera map.

Snow, who is commonly considered to be the father of modern epidemiology, is most famous for identifying where cases of cholera were occurring during an epidemic in London in 1854. This allowed him to trace the source of the outbreak – a contaminated water pump on Broad Street.

Today, very few cases of cholera are reported in the UK; however, it is endemic in many other countries and resulted in more than 100 000 deaths in 2010. It is caused by the bacterium Vibrio cholerae, which produces toxins in the small intestine of an infected person, causing them – if untreated – to produce more than ten litres of diarrhoea a day. Death comes as a result of dehydration.

As shown by Snow in 1854, people get the disease through drinking contaminated water. This is a real problem in much of the world, where clean drinking water is not accessible for local populations.

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Written by Benjamin Thompson

23/04/2012 at 8:10 pm